ChemInform Abstract: [3 + 2] Cycloaddition of Fischer Alkenyl Carbene Complexes to Enamines: An Efficient Asymmetric Approach to Cyclopentanoids.
- Barluenga, Jose 1
- Tomas, Miguel 1
- Ballesteros, Alfredo 1
- Santamaria, Javier 1
- Brillet, Cecile 1
- Garcia-Granda, Santiago 1
- Pinera-Nicolas, Alejandro 1
- Vazquez, Jesus T. 1
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1
Universidad de Oviedo
info
ISSN: 0931-7597, 1522-2667
Datum der Publikation: 2010
Ausgabe: 30
Nummer: 35
Seiten: no-no
Art: Artikel
Andere Publikationen in: ChemInform
Zusammenfassung
High regio- and stereoselectivities are observed in cycloaddition reactions of Fisher carbene complexes to enamines which provide a new protocol for the synthesis of cyclopentane derivatives. The cycloaddition of enamine (X) with carbene complex (VIIc) bearing a bulky alkoxy group yields exclusively adduct (XI) while regioisomeric mixtures (ca. 2:1, not shown) are formed from other carbene complexes with this enamine.
Bibliographische Referenzen
- Barluenga, (1999), J. Am. Chem. Soc., 121, pp. 4516, 10.1021/ja9825736