Publicaciones en colaboración con investigadores/as de University of York (19)

2023

  1. Comparing the Catalytic and Structural Characteristics of a ‘Short’ Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli

    ChemBioChem, Vol. 24, Núm. 1

  2. Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms

    Acta crystallographica. Section F, Structural biology communications, Vol. 79, pp. 224-230

2022

  1. Multifunctional biocatalyst for conjugate reduction and reductive amination

    Nature, Vol. 604, Núm. 7904, pp. 86-91

2021

  1. The Reactivity of α-Fluoroketones with PLP Dependent Enzymes: Transaminases as Hydrodefluorinases

    ChemCatChem, Vol. 13, Núm. 18, pp. 3967-3972

2020

  1. Asymmetric Synthesis of Primary and Secondary β-Fluoro-arylamines using Reductive Aminases from Fungi

    ChemCatChem, Vol. 12, Núm. 9, pp. 2421-2425

  2. Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases

    Chemical Science, Vol. 11, Núm. 19, pp. 5052-5057

  3. Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Using Noncovalent Mechanisms

    ACS Catalysis, Vol. 10, Núm. 19, pp. 11136-11146

2019

  1. S-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation

    Angewandte Chemie - International Edition, Vol. 58, Núm. 49, pp. 17583-17588

2018

  1. A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

    ACS Catalysis, Vol. 8, Núm. 12, pp. 11534-11541

  2. The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

    Angewandte Chemie - International Edition, Vol. 57, Núm. 36, pp. 11584-11588

2017

  1. A reductive aminase from Aspergillus oryzae

    Nature Chemistry, Vol. 9, Núm. 10, pp. 961-969

  2. Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines

    Angewandte Chemie - International Edition, Vol. 56, Núm. 49, pp. 15589-15593

  3. Imine reductases (IREDs)

    Current Opinion in Chemical Biology, Vol. 37, pp. 19-25

  4. NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

    Advanced Synthesis and Catalysis, Vol. 359, Núm. 12, pp. 2011-2025

2016

  1. Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination

    Angewandte Chemie - International Edition, Vol. 55, Núm. 9, pp. 3144-3147

  2. Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue

    ChemBioChem, Vol. 17, Núm. 24, pp. 2308-2311

2014

  1. Structures of alcohol dehydrogenases from Ralstonia and Sphingobium spp. Reveal the molecular basis for their recognition of 'bulky-bulky' ketones

    Topics in Catalysis, Vol. 57, Núm. 5, pp. 356-365

2013

  1. Structure and activity of NADPH-dependent reductase Q1EQE0 from streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate

    ChemBioChem, Vol. 14, Núm. 11, pp. 1372-1379

2012

  1. Structures of a γ-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct

    Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 68, Núm. 10, pp. 1175-1180