Publicaciones en las que colabora con SAUL MARTINEZ MONTERO (21)

2023

  1. New Oligonucleotide 2¢-O-Alkyl N3¢/P5¢ (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity

    Nucleic Acid Therapeutics, Vol. 33, Núm. 5, pp. 319-328

2019

  1. Effect of sugar 2′,4′-modifications on gene silencing activity of sirna duplexes

    Nucleic Acid Therapeutics, Vol. 29, Núm. 4, pp. 187-194

2018

  1. Adjusting the Structure of 2′-Modified Nucleosides and Oligonucleotides via C4′-α-F or C4′-α-OMe Substitution: Synthesis and Conformational Analysis

    Journal of Organic Chemistry, Vol. 83, Núm. 17, pp. 9839-9849

  2. Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells

    Molecular Therapy - Nucleic Acids, Vol. 11, pp. 518-527

2017

  1. 4′-C-Methoxy-2′-deoxy-2′-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing

    Journal of the American Chemical Society, Vol. 139, Núm. 41, pp. 14542-14555

  2. Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2?-O methylations

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 11, pp. E2106-E2115

2016

  1. Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells

    Molecular Therapy - Nucleic Acids, Vol. 5, pp. e364

2015

  1. Locked 2′-Deoxy-2′,4′-Difluororibo Modified Nucleic Acids: Thermal Stability, Structural Studies, and siRNA Activity

    ACS Chemical Biology, Vol. 10, Núm. 9, pp. 2016-2023

  2. Nucleotide Sugar Pucker Preference Mitigates Excision by HIV-1 RT

    ACS Chemical Biology, Vol. 10, Núm. 9, pp. 2024-2033

  3. Seven-Membered Ring Nucleoside Analogues: Stereoselective Synthesis and Studies on Their Conformational Properties

    Organic Letters, Vol. 17, Núm. 21, pp. 5416-5419

  4. Synthesis and properties of 2′-deoxy-2′,4′-difluoroarabinose-modified nucleic acids

    Journal of Organic Chemistry, Vol. 80, Núm. 6, pp. 3083-3091

  5. Synthesis, Structure, and Conformational Analysis of Nucleoside Analogues Comprising Six-Membered 1,3-Oxathiane Sugar Rings

    European Journal of Organic Chemistry, Vol. 2015, Núm. 9, pp. 1945-1953

2014

  1. Rigid 2′,4′-difluororibonucleosides: Synthesis, conformational analysis, and incorporation into nascent RNA by HCV polymerase

    Journal of Organic Chemistry, Vol. 79, Núm. 12, pp. 5627-5635

2012

  1. CAL-B-catalyzed acylation of nucleosides and role of the sugar conformation: An improved understanding of the enzyme-substrate recognition

    European Journal of Organic Chemistry, pp. 5483-5490

  2. Design and divergent synthesis of aza nucleosides from a chiral imino sugar

    Journal of Organic Chemistry, Vol. 77, Núm. 10, pp. 4671-4678

  3. Sintésis de nucleósidos con aplicaciones terapéuticas: preparación quimioenzimática de precursores de oligonucleótidos y azanucleósidos

    Sintésis de nucleósidos con aplicaciones terapéuticas: preparación quimioenzimática de precursores de oligonucleótidos y azanucleósidos

  4. Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides

    Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 23, pp. 6885-6893

2011

  1. An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis

    Organic and Biomolecular Chemistry, Vol. 9, Núm. 17, pp. 5960-5966

2010

  1. Chemoenzymatic synthesis of 3′-O-acetal-protected 2′-deoxynucleosides as building blocks for nucleic acid chemistry

    European Journal of Organic Chemistry, pp. 1736-1744

  2. Enzymatic parallel kinetic resolution of mixtures of d / l 2′-deoxy and ribonucleosides: An approach for the isolation of β- L -nucleosides

    Journal of Organic Chemistry, Vol. 75, Núm. 19, pp. 6605-6613