Publicaciones en las que colabora con Ignacio Varela Egocheaga (15)

2021

  1. Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia

    Journal of Clinical Investigation, Vol. 131, Núm. 13

2020

  1. The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells

    Journal of Biological Chemistry, Vol. 295, Núm. 7, pp. 2001-2017

2011

  1. Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53

    EMBO Journal, Vol. 30, Núm. 11, pp. 2219-2232

  2. Hutchinson-Gilford progeria: Splicing-directed therapy in a new mouse model of human accelerated aging

    Science Translational Medicine, Vol. 3, Núm. 106

2010

  1. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

    Aging Cell, Vol. 9, Núm. 6, pp. 947-957

2008

  1. Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

    Nature Medicine, Vol. 14, Núm. 7, pp. 767-772

  2. Envejecimiento acelerado y supresion tumoral: conexiones moleculares y oportunidades terapeuticas derivadas del estudio de ratones deficientes en la metaloproteasa face1/zmpste24

    Envejecimiento acelerado y supresion tumoral: conexiones moleculares y oportunidades terapeuticas derivadas del estudio de ratones deficientes en la metaloproteasa face1/zmpste24

  3. Microcephalia with mandibular and dental dysplasia in adult Zmpste24-deficient mice

    Journal of Anatomy, Vol. 213, Núm. 5, pp. 509-519

  4. Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

    Journal of Cell Biology, Vol. 181, Núm. 1, pp. 27-35

  5. Premature aging in mice activates a systemic metabolic response involving autophagy induction

    Human Molecular Genetics, Vol. 17, Núm. 14, pp. 2196-2211

2007

  1. Human progeroid syndromes, aging and cancer: New genetic and epigenetic insights into old questions

    Cellular and Molecular Life Sciences, Vol. 64, Núm. 2, pp. 155-170

2005

  1. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation

    Nature, Vol. 437, Núm. 7058, pp. 564-568

  2. From immature lamin to premature aging: Molecular pathways and therapeutic opportunities

    Cell Cycle, Vol. 4, Núm. 12, pp. 1732-1735

2003

  1. AtFACE-2, a functional Prenylated Protein Protease from Arabidopsis thaliana Related to Mammalian Ras-converting Enzymes

    Journal of Biological Chemistry, Vol. 278, Núm. 43, pp. 42091-42097

  2. Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans

    Biochemical Journal, Vol. 370, Núm. 3, pp. 1047-1054