Bioquímica y Biología Molecular
Department
Francisco
Barros de la Roza
Publications by the researcher in collaboration with Francisco Barros de la Roza (47)
2021
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Influence of Kv11.1 (hERG1) K+ channel expression on DNA damage induced by the genotoxic agent methyl methanesulfonate
Pflugers Archiv European Journal of Physiology, Vol. 473, Núm. 2, pp. 197-217
2020
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The EAG Voltage-Dependent K+ Channel Subfamily: Similarities and Differences in Structural Organization and Gating
Frontiers in Pharmacology, Vol. 11
2019
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New structures and gating of voltage-dependent potassium (Kv) channels and their relatives: A multi-domain and dynamic question
International Journal of Molecular Sciences, Vol. 20, Núm. 2
2018
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Gating mechanism of Kv11.1 (hERG) K + channels without covalent connection between voltage sensor and pore domains
Pflugers Archiv European Journal of Physiology, Vol. 470, Núm. 3, pp. 517-536
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Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain
Pflugers Archiv European Journal of Physiology, Vol. 470, Núm. 7, pp. 1069-1085
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Relative positioning of Kv11.1 (hERG) K+ channel cytoplasmic domain-located fluorescent tags toward the plasma membrane
Scientific Reports, Vol. 8, Núm. 1
2015
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ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells
Cellular Signalling, Vol. 27, Núm. 9, pp. 1720-1730
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Interactions between the N-terminal tail and the gating machinery of hERG K+ channels both in closed and open/inactive states
Pflugers Archiv European Journal of Physiology, Vol. 467, Núm. 8, pp. 1747-1756
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Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains
Nature Communications, Vol. 6
2013
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Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels
Biochemical Journal, Vol. 451, Núm. 3, pp. 463-474
2012
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An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain
Journal of Pharmacology and Experimental Therapeutics, Vol. 341, Núm. 3, pp. 634-645
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Cell type influences the molecular mechanisms involved in hormonal regulation of ERG K+ channels
Pflugers Archiv European Journal of Physiology, Vol. 463, Núm. 5, pp. 685-702
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Cytoplasmic domains and voltage-dependent potassium channel gating
Frontiers in Pharmacology, Vol. 3 MAR
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Screening for mutations in Spanish families with myotonia. Functional analysis of novel mutations in CLCN1 gene
Neuromuscular Disorders, Vol. 22, Núm. 3, pp. 231-243
2011
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Demonstration of physical proximity between the n terminus and the S4-S5 linker of the human ether-à-go-go-related gene (hERG) potassium channel
Journal of Biological Chemistry, Vol. 286, Núm. 21, pp. 19065-19075
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Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating
PLoS ONE, Vol. 6, Núm. 9
2009
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Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor
Pflugers Archiv European Journal of Physiology, Vol. 457, Núm. 6, pp. 1237-1252
2008
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FRET with multiply labeled HERG K+ channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1783, Núm. 10, pp. 1681-1699
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Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions
Biophysical Journal, Vol. 94, Núm. 10, pp. 3893-3911
2005
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Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells
Journal of Physiology, Vol. 566, Núm. 3, pp. 717-736