Publicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (108)

2023

  1. A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features

    Blood, Vol. 142, Núm. 20, pp. 1752-1756

  2. The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

    Nature Communications, Vol. 14, Núm. 1

2021

  1. Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse

    Molecular Biology and Evolution, Vol. 38, Núm. 8, pp. 3415-3435

  2. Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia

    Journal of Clinical Investigation, Vol. 131, Núm. 13

2020

  1. Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

    Nature Cell Biology, Vol. 22, Núm. 10, pp. 1223-1238

  2. Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

    Blood, Vol. 136, Núm. 3, pp. 313-327

2019

  1. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

    Nucleic Acids Research, Vol. 47, Núm. 10, pp. 5016-5037

2018

  1. TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

    Nature Communications, Vol. 9, Núm. 1

2017

  1. Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

    Stem Cell Research, Vol. 21, pp. 137-140

  2. Multilayer OMIC Data in medullary thyroid carcinoma identifies the STAT3 pathway as a potential therapeutic target in RETM918T Tumors

    Clinical Cancer Research, Vol. 23, Núm. 5, pp. 1334-1345

2016

  1. DNMT1 inhibition reprograms pancreatic cancer stem cells via upregulation of the miR-17-92 cluster

    Cancer Research, Vol. 76, Núm. 15, pp. 4546-4558

  2. Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency

    Stem Cell Reports, Vol. 7, Núm. 4, pp. 602-618

2015

  1. Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer

    Oncotarget, Vol. 6, Núm. 8, pp. 5903-5917

2014

  1. LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk

    Epigenetics, Vol. 9, Núm. 11, pp. 1532-1539

  2. LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk

    British Journal of Cancer, Vol. 110, Núm. 8, pp. 2123-2130

  3. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia

    Nature Communications, Vol. 5

2013

  1. DNA methylation signatures identify biologically distinct thyroid cancer subtypes

    Journal of Clinical Endocrinology and Metabolism, Vol. 98, Núm. 7, pp. 2811-2821

  2. Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA

    Environmental Health Perspectives, Vol. 121, Núm. 6, pp. 650-656

2012

  1. A DNA methylation fingerprint of 1628 human samples

    Genome Research, Vol. 22, Núm. 2, pp. 407-419

  2. Distinct DNA methylomes of newborns and centenarians

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 26, pp. 10522-10527