Biología de Organismos y Sistemas
Department
Clara
Bueno Uroz
Publications by the researcher in collaboration with Clara Bueno Uroz (17)
2024
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NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression
Blood, Vol. 144, Núm. 19, pp. 2002-2017
2023
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
2021
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Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia
Journal of Clinical Investigation, Vol. 131, Núm. 13
2020
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Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL
Blood, Vol. 136, Núm. 3, pp. 313-327
2019
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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment
Nucleic Acids Research, Vol. 47, Núm. 10, pp. 5016-5037
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Corrigendum: H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
Genome research
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Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL
Blood
2018
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Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation
Epigenomics, Vol. 10, Núm. 7, pp. 903-924
2017
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Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus
Stem Cell Research, Vol. 21, pp. 137-140
2016
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Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
Stem Cell Reports, Vol. 7, Núm. 4, pp. 602-618
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα
Leukemia, Vol. 30, Núm. 3, pp. 674-682
2015
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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
Genome Research, Vol. 25, Núm. 1, pp. 27-40
2014
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Role of BRD4 in hematopoietic differentiation of embryonic stem cells
Epigenetics, Vol. 9, Núm. 4, pp. 566-578
2012
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A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification
Cell Research, Vol. 22, Núm. 6, pp. 986-1002
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A promoter DNA demethylation landscape of human hematopoietic differentiation
Nucleic Acids Research, Vol. 40, Núm. 1, pp. 116-131
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Maintenance of human embryonic stem cells in mesenchymal stem cell-conditioned media augments hematopoietic specification
Stem Cells and Development, Vol. 21, Núm. 9, pp. 1549-1558
2008
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Cancer genes hypermethylated in human embryonic stem cells
PLoS ONE, Vol. 3, Núm. 9