ALFREDO JAVIER
FERNANDEZ BRAÑA
Investigador/a
MARIA DEL CARMEN
MENDEZ FERNANDEZ
Catedrática de Universidad
Publicaciones en las que colabora con MARIA DEL CARMEN MENDEZ FERNANDEZ (88)
2023
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Uncovering the Cryptic Gene Cluster ahb for 3-amino-4-hydroxybenzoate Derived Ahbamycins, by Searching SARP Regulator Encoding Genes in the Streptomyces argillaceus Genome
International Journal of Molecular Sciences, Vol. 24, Núm. 9
2022
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Combinatorial biosynthesis yields novel hybrid argimycin P alkaloids with diverse scaffolds in Streptomyces argillaceus
Microbial Biotechnology, Vol. 15, Núm. 12, pp. 2905-2916
2020
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Discovery of Cryptic Largimycins in Streptomyces Reveals Novel Biosynthetic Avenues Enriching the Structural Diversity of the Leinamycin Family
ACS chemical biology, Vol. 15, Núm. 6, pp. 1541-1553
2018
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Characterization of the jomthonic acids biosynthesis pathway and isolation of novel analogues in streptomyces caniferus GUA-06-05-006A
Marine Drugs, Vol. 16, Núm. 8
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New insights into the biosynthesis pathway of polyketide alkaloid argimycins P in Streptomyces argillaceus
Frontiers in Microbiology, Vol. 9, Núm. FEB
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Searching for glycosylated natural products in actinomycetes and identification of novel macrolactams and angucyclines
Frontiers in Microbiology, Vol. 9, Núm. JAN
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Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches
PLoS ONE, Vol. 13, Núm. 5
2017
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Caboxamycin biosynthesis pathway and identification of novel benzoxazoles produced by cross-talk in Streptomyces sp. NTK 937
Microbial Biotechnology, Vol. 10, Núm. 4, pp. 873-885
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Identification by genome mining of a type I polyketide gene cluster from Streptomyces argillaceus involved in the biosynthesis of pyridine and piperidine alkaloids argimycins P
Frontiers in Microbiology, Vol. 8, Núm. FEB
2016
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Characterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: Generation of a novel improved derivative
Microbial Cell Factories, Vol. 15, Núm. 1
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Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives
Microbial Cell Factories, Vol. 15, Núm. 1
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Increasing antibiotic production yields by favoring the biosynthesis of precursor metabolites glucose-1-phosphate and/or malonyl-CoA in Streptomyces producer strains
Journal of Antibiotics
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Laccase-catalysed biotransformation of collismycin derivatives. A novel enzymatic approach for the cleavage of oximes
Green Chemistry
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New insights into paulomycin biosynthesis pathway in Streptomyces albus J1074 and generation of novel derivatives by combinatorial biosynthesis
Microbial Cell Factories, Vol. 15, Núm. 1
2015
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Crosstalk of Nataxazole Pathway with Chorismate-Derived Ionophore Biosynthesis Pathways in Streptomyces sp. Tü 6176
ChemBioChem, Vol. 16, Núm. 13, pp. 1925-1932
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Genome Mining of Streptomyces sp. Tü 6176: Characterization of the Nataxazole Biosynthesis Pathway
ChemBioChem, Vol. 16, Núm. 10, pp. 1461-1473
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Transcriptional regulation of mithramycin biosynthesis in Streptomyces argillaceus: Dual role as activator and repressor of the PadR-like regulator MtrY
Microbiology (United Kingdom), Vol. 161, Núm. 2, pp. 272-284
2014
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Activation and identification of five clusters for secondary metabolites in Streptomyces albusJ1074
Microbial Biotechnology, Vol. 7, Núm. 3, pp. 242-256
2013
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Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus
Metabolic Engineering, Vol. 20, pp. 187-197
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Engineering the biosynthesis of the polyketide-nonribosomal peptide collismycin A for generation of analogs with neuroprotective activity
Chemistry and Biology, Vol. 20, Núm. 8, pp. 1022-1032