DANIEL
ZABALA ALVAREZ
Investigador/a en el periodo 2013-2020
Publicaciones (7) Publicaciones de DANIEL ZABALA ALVAREZ
2020
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Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin
Microbial Cell Factories, Vol. 19, Núm. 1
2019
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Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group
ACS Chemical Biology, Vol. 14, Núm. 6, pp. 1305-1309
2017
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Identification by genome mining of a type I polyketide gene cluster from Streptomyces argillaceus involved in the biosynthesis of pyridine and piperidine alkaloids argimycins P
Frontiers in Microbiology, Vol. 8, Núm. FEB
2016
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A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors
Journal of the American Chemical Society, Vol. 138, Núm. 13, pp. 4342-4345
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Increasing antibiotic production yields by favoring the biosynthesis of precursor metabolites glucose-1-phosphate and/or malonyl-CoA in Streptomyces producer strains
Journal of Antibiotics
2015
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Transcriptional regulation of mithramycin biosynthesis in Streptomyces argillaceus: Dual role as activator and repressor of the PadR-like regulator MtrY
Microbiology (United Kingdom), Vol. 161, Núm. 2, pp. 272-284
2013
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Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus
Metabolic Engineering, Vol. 20, pp. 187-197