Publications (110) Publications de JOSE MARIA PEREZ FREIJE

2024

  1. Assessing microbiota composition in the context of aging

    Methods in Cell Biology (Academic Press Inc.), pp. 73-85

  2. Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing

    iScience, Vol. 27, Núm. 6

  3. Noncoding RNA Contribution to Aging and Lifespan

    The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 79, Núm. 4

  4. The hallmarks of aging as a conceptual framework for health and longevity research

    Frontiers in Aging, Vol. 5

2023

  1. USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy

    Cell Death and Disease, Vol. 14, Núm. 1

2022

  1. Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells

    EMBO Journal, Vol. 41, Núm. 21

2020

  1. Ubiquitin-specific proteases as targets for anticancer drug therapies

    Cancer-Leading Proteases: Structures, Functions, and Inhibition (Elsevier), pp. 73-120

2019

  1. Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome

    Nature Medicine, Vol. 25, Núm. 3, pp. 423-426

  2. Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

    Nature Medicine

  3. Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207)

    Nature Cell Biology

2018

  1. Erratum: Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses (Journal of Biological Chemistry (2018) 293 :30 (11970–11970) DOI : 10.1074/jbc.AAC118.004704)

    Journal of Biological Chemistry

  2. Loss of the deubiquitinase usp36 destabilizes the rna helicase dhx33 and causes preimplantation lethality in mice

    Journal of Biological Chemistry, Vol. 293, Núm. 6, pp. 2183-2194

  3. Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

    Cell Reports, Vol. 24, Núm. 9, pp. 2392-2403

  4. Protease silencing to explore the molecular mechanisms of cancer and aging

    Methods in Molecular Biology (Humana Press Inc.), pp. 261-269

  5. The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

    PLoS Biology, Vol. 16, Núm. 10

2017

  1. Deubiquitination in cancer stem cells

    Aging

  2. Functional relevance of deubiquitinases in life and disease

    Proteases in Physiology and Pathology (Springer Singapore), pp. 355-382

  3. USP39 deubiquitinase is essential for KRAS oncogene-driven cancer

    Journal of Biological Chemistry, Vol. 292, Núm. 10, pp. 4164-4175

2016

  1. Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype

    Journal of Clinical Investigation, Vol. 126, Núm. 10, pp. 3879-3893

  2. Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling

    Nature Medicine, Vol. 22, Núm. 1, pp. 91-96