Publications (200) Publications de MARIA DEL CARMEN MENDEZ FERNANDEZ

2024

  1. Unearthing a Cryptic Biosynthetic Gene Cluster for the Piperazic Acid-Bearing Depsipeptide Diperamycin in the Ant-Dweller Streptomyces sp. CS113

    International Journal of Molecular Sciences, Vol. 25, Núm. 4

  2. Volatilome: Smells like microbial spirit

    Advances in Applied Microbiology (Academic Press Inc.)

2023

  1. Co-Expression of Transcriptional Regulators and Housekeeping Genes in Streptomyces spp.: A Strategy to Optimize Metabolite Production

    Microorganisms, Vol. 11, Núm. 6

  2. Identification of the Biosynthetic Gene Cluster of New Piperazic Acid-Containing Lipopeptides with Cytotoxic Activity in the Genome of Marine Streptomyces PHM034

    Metabolites, Vol. 13, Núm. 10

  3. The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties

    Microorganisms, Vol. 11, Núm. 7

  4. Uncovering the Cryptic Gene Cluster ahb for 3-amino-4-hydroxybenzoate Derived Ahbamycins, by Searching SARP Regulator Encoding Genes in the Streptomyces argillaceus Genome

    International Journal of Molecular Sciences, Vol. 24, Núm. 9

2022

  1. Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β-Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family

    ACS Chemical Biology, Vol. 17, Núm. 8, pp. 2320-2331

  2. Colibrimycins, Novel Halogenated Hybrid Polyketide Synthase- Nonribosomal Peptide Synthetase (PKS-NRPS) Compounds Produced by Streptomyces sp. Strain CS147

    Applied and Environmental Microbiology, Vol. 88, Núm. 1

  3. Combinatorial biosynthesis yields novel hybrid argimycin P alkaloids with diverse scaffolds in Streptomyces argillaceus

    Microbial Biotechnology, Vol. 15, Núm. 12, pp. 2905-2916

  4. Volatile Compounds in Actinomycete Communities: A New Tool for Biosynthetic Gene Cluster Activation, Cooperative Growth Promotion, and Drug Discovery

    Cells, Vol. 11, Núm. 21

2021

  1. A multidisciplinary approach to unraveling the natural product biosynthetic potential of a streptomyces strain collection isolated from leaf-cutting ants

    Microorganisms, Vol. 9, Núm. 11

  2. A novel LysR-type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

    Engineering in Life Sciences, Vol. 21, Núm. 1-2, pp. 4-18

  3. Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A

    Angewandte Chemie - International Edition, Vol. 60, Núm. 24, pp. 13536-13541

2020

  1. Discovery of Cryptic Largimycins in Streptomyces Reveals Novel Biosynthetic Avenues Enriching the Structural Diversity of the Leinamycin Family

    ACS chemical biology, Vol. 15, Núm. 6, pp. 1541-1553

  2. Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin

    Microbial Cell Factories, Vol. 19, Núm. 1

  3. Identificación y caracterización de agrupamientos de genes de biosíntesis de compuestos derivados de hidroxibenzoatos en Streptomyces

    Universidad, investigación y conocimiento: el valor de la I+D+i para evolucionar hacia una sociedad sostenible y responsable (Universidad de Oviedo), pp. 109-114

  4. New sipanmycin analogues generated by combinatorial biosynthesis and mutasynthesis approaches relying on the substrate flexibility of key enzymes in the biosynthetic pathway

    Applied and Environmental Microbiology, Vol. 86, Núm. 3

2018

  1. Characterization of the jomthonic acids biosynthesis pathway and isolation of novel analogues in streptomyces caniferus GUA-06-05-006A

    Marine Drugs, Vol. 16, Núm. 8

  2. Cooperative involvement of glycosyltransferases in the transfer of amino sugars during the biosynthesis of the macrolactam sipanmycin by Streptomyces sp. strain CS149

    Applied and Environmental Microbiology, Vol. 84, Núm. 18

  3. New insights into the biosynthesis pathway of polyketide alkaloid argimycins P in Streptomyces argillaceus

    Frontiers in Microbiology, Vol. 9, Núm. FEB