CARLOS
LOPEZ OTIN
Catedrático de Universidad
Centro de Investigación Biomédica en Red de Cáncer
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigación Biomédica en Red de Cáncer (28)
2024
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Assessing microbiota composition in the context of aging
Methods in Cell Biology (Academic Press Inc.), pp. 73-85
2023
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Exercise sustains the hallmarks of health
Journal of Sport and Health Science, Vol. 12, Núm. 1, pp. 8-35
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Hallmarks of aging: An expanding universe
Cell, Vol. 186, Núm. 2, pp. 243-278
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Meta-hallmarks of aging and cancer
Cell Metabolism, Vol. 35, Núm. 1, pp. 12-35
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USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
Cell Death and Disease, Vol. 14, Núm. 1
2022
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Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells
EMBO Journal, Vol. 41, Núm. 21
2021
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Autophagy in major human diseases
EMBO Journal, Vol. 40, Núm. 19
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Correction to: ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration (Cell Death & Differentiation, (2021), 28, 9, (2651-2672), 10.1038/s41418-021-00776-1)
Cell Death and Differentiation
2020
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Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling
Biological Psychiatry, Vol. 87, Núm. 2, pp. 100-112
2019
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Association of the POT1 Germline Missense Variant p.I78T with Familial Melanoma
JAMA Dermatology, Vol. 155, Núm. 5, pp. 604-609
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CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D12 mantle cell lymphoma
Blood, Vol. 133, Núm. 9, pp. 940-951
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Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
Nature Medicine, Vol. 25, Núm. 3, pp. 423-426
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Genome Sequencing and Analysis Methods in Chronic Lymphocytic Leukemia
Methods in Molecular Biology (Humana Press Inc.), pp. 319-325
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Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Nature Medicine
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Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics
Nature Communications, Vol. 10, Núm. 1
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Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
Autophagy
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The U1 spliceosomal RNA is recurrently mutated in multiple cancers
Nature, Vol. 574, Núm. 7780, pp. 712-716
2018
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Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia
Blood, Vol. 132, Núm. 22, pp. 2375-2388
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Carbotoxicity—Noxious Effects of Carbohydrates
Cell, Vol. 175, Núm. 3, pp. 605-614
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Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver
Aging Cell, Vol. 17, Núm. 3