Publicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Cardiovasculares Carlos III (21)

2023

  1. USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy

    Cell Death and Disease, Vol. 14, Núm. 1

2022

  1. Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells

    EMBO Journal, Vol. 41, Núm. 21

2020

  1. Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging

    Aging Cell, Vol. 19, Núm. 9

2019

  1. Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells

    EMBO Molecular Medicine, Vol. 11, Núm. 4

  2. Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

    Cell Stem Cell, Vol. 25, Núm. 3, pp. 407-418.e6

2018

  1. Ablation of the stress protease OMA1 protects against heart failure in mice

    Science Translational Medicine, Vol. 10, Núm. 434

  2. The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

    PLoS Biology, Vol. 16, Núm. 10

  3. Vascular smooth muscle–specific progerin expression accelerates atherosclerosis and death in a mouse model of Hutchinson-Gilford progeria syndrome

    Circulation, Vol. 138, Núm. 3, pp. 266-282

2016

  1. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 46, pp. E7250-E7259

  2. Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling

    Nature Medicine, Vol. 22, Núm. 1, pp. 91-96

  3. MMP-25 metalloprotease regulates innate immune response through NF-κB signaling

    Journal of Immunology, Vol. 197, Núm. 1, pp. 296-302

2014

  1. ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

    Cell Reports, Vol. 8, Núm. 2, pp. 542-556

  2. Exosomes and autophagy: Coordinated mechanisms for the maintenance of cellular fitness

    Frontiers in Immunology, Vol. 5, Núm. AUG

  3. Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation

    Science Signaling, Vol. 7, Núm. 322

2013

  1. Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

    Circulation, Vol. 127, Núm. 24, pp. 2442-2451

  2. Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture

    Journal of Proteomics, Vol. 91, pp. 466-477

  3. Supercomplex assembly determines electron flux in the mitochondrial electron transport chain

    Science, Vol. 340, Núm. 6140, pp. 1567-1570

2012

  1. Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

    EMBO Journal, Vol. 31, Núm. 9, pp. 2117-2133

2011

  1. Hutchinson-Gilford progeria: Splicing-directed therapy in a new mouse model of human accelerated aging

    Science Translational Medicine, Vol. 3, Núm. 106

2008

  1. Nitric oxide elicits functional MMP-13 protein-tyrosine nitration during wound repair

    FASEB Journal, Vol. 22, Núm. 9, pp. 3207-3215