CARLOS
LOPEZ OTIN
Catedrático de Universidad
JOSE MARIA
PEREZ FREIJE
Catedrático de Universidad
Publikationen, an denen er mitarbeitet JOSE MARIA PEREZ FREIJE (88)
2024
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Assessing microbiota composition in the context of aging
Methods in Cell Biology (Academic Press Inc.), pp. 73-85
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Noncoding RNA Contribution to Aging and Lifespan
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 79, Núm. 4
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The hallmarks of aging as a conceptual framework for health and longevity research
Frontiers in Aging, Vol. 5
2023
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USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
Cell Death and Disease, Vol. 14, Núm. 1
2022
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Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells
EMBO Journal, Vol. 41, Núm. 21
2020
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Ubiquitin-specific proteases as targets for anticancer drug therapies
Cancer-Leading Proteases: Structures, Functions, and Inhibition (Elsevier), pp. 73-120
2019
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Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
Nature Medicine, Vol. 25, Núm. 3, pp. 423-426
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Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Nature Medicine
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Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207)
Nature Cell Biology
2018
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Erratum: Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses (Journal of Biological Chemistry (2018) 293 :30 (11970–11970) DOI : 10.1074/jbc.AAC118.004704)
Journal of Biological Chemistry
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Loss of the deubiquitinase usp36 destabilizes the rna helicase dhx33 and causes preimplantation lethality in mice
Journal of Biological Chemistry, Vol. 293, Núm. 6, pp. 2183-2194
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Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
Cell Reports, Vol. 24, Núm. 9, pp. 2392-2403
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The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function
PLoS Biology, Vol. 16, Núm. 10
2017
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Functional relevance of deubiquitinases in life and disease
Proteases in Physiology and Pathology (Springer Singapore), pp. 355-382
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USP39 deubiquitinase is essential for KRAS oncogene-driven cancer
Journal of Biological Chemistry, Vol. 292, Núm. 10, pp. 4164-4175
2016
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Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
Journal of Clinical Investigation, Vol. 126, Núm. 10, pp. 3879-3893
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Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling
Nature Medicine, Vol. 22, Núm. 1, pp. 91-96
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Metabolic Control of Longevity
Cell, Vol. 166, Núm. 4, pp. 802-821
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NF-κB signaling as a driver of ageing
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 133-174
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The novel tumor suppressor AIRAPL regulates IGF1R proteostasis
Cell Cycle