CARLOS
LOPEZ OTIN
Catedrático de Universidad
ALEJANDRO
PIÑEIRO UGALDE
Investigador
Publicaciones en las que colabora con ALEJANDRO PIÑEIRO UGALDE (18)
2024
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Noncoding RNA Contribution to Aging and Lifespan
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 79, Núm. 4
2022
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Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells
EMBO Journal, Vol. 41, Núm. 21
2018
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The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function
PLoS Biology, Vol. 16, Núm. 10
2014
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The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
Genes and Development, Vol. 28, Núm. 7, pp. 765-782
2013
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Aminopeptidase O
Handbook of Proteolytic Enzymes (Elsevier Ltd), pp. 438-442
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Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion
Nature Communications, Vol. 4
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The Emergence of Geromirs: A Group of microRNAs Implicated in Aging
MicroRNAs in Medicine (Wiley Blackwell), pp. 77-89
2011
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Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53
EMBO Journal, Vol. 30, Núm. 11, pp. 2219-2232
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Cell autonomous and systemic factors in progeria development
Biochemical Society Transactions
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Micromanaging aging with miRNAs: New messages from the nuclear envelope
Nucleus, Vol. 2, Núm. 6, pp. 549-555
2010
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Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Núm. 37, pp. 16268-16273
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Metalloproteases and the degradome.
Methods in molecular biology (Clifton, N.J.), Vol. 622, pp. 3-29
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Rejuvenating somatotropic signaling: A therapeutical opportunity for premature aging?
Aging, Vol. 2, Núm. 12, pp. 1017-1022
2008
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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Nature Medicine, Vol. 14, Núm. 7, pp. 767-772
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Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
Journal of Cell Biology, Vol. 181, Núm. 1, pp. 27-35
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Premature aging in mice activates a systemic metabolic response involving autophagy induction
Human Molecular Genetics, Vol. 17, Núm. 14, pp. 2196-2211
2005
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Identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in archaea
Journal of Biological Chemistry, Vol. 280, Núm. 34, pp. 30367-30375
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Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase
Journal of Biological Chemistry, Vol. 280, Núm. 14, pp. 14310-14317