MARIO
FERNANDEZ FRAGA
Profesor Asociado
Hospital Universitario Central de Asturias
Oviedo, EspañaPublicaciones en colaboración con investigadores/as de Hospital Universitario Central de Asturias (48)
2024
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A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma
eBioMedicine, Vol. 102
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Metformin and Glucose Concentration as Limiting Factors in Retinal Pigment Epithelial Cell Viability and Proliferation
International Journal of Molecular Sciences, Vol. 25, Núm. 5
2023
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Circulating miRNA expression in long-standing type 1 diabetes mellitus
Scientific Reports, Vol. 13, Núm. 1
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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma
Nature Communications, Vol. 14, Núm. 1
2022
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Classification of follicular-patterned thyroid lesions using a minimal set of epigenetic biomarkers
European journal of endocrinology, Vol. 187, Núm. 3, pp. 335-347
2021
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Dna methylomes and epigenetic age acceleration associations with poor metabolic control in t1d
Biomedicines, Vol. 9, Núm. 1, pp. 1-8
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Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma
Frontiers in Cell and Developmental Biology, Vol. 9
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Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia
Journal of Clinical Investigation, Vol. 131, Núm. 13
2020
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Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis
International Journal of Cancer, Vol. 146, Núm. 2, pp. 373-387
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Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases
Nature Cell Biology, Vol. 22, Núm. 10, pp. 1223-1238
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No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells
Epigenetics, Vol. 15, Núm. 3, pp. 283-293
2019
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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment
Nucleic Acids Research, Vol. 47, Núm. 10, pp. 5016-5037
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Epigenetic Deregulation of Protocadherin PCDHGC3 in Pheochromocytomas/Paragangliomas Associated With SDHB Mutations
The Journal of clinical endocrinology and metabolism, Vol. 104, Núm. 11, pp. 5673-5692
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Epigenetics and Lifestyle: The Impact of Stress, Diet, and Social Habits on Tissue Homeostasis
Epigenetics and Regeneration (Elsevier), pp. 461-489
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Epigenetics in cancer therapy and nanomedicine
Clinical Epigenetics, Vol. 11, Núm. 1
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Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes
Journal of Translational Medicine, Vol. 17, Núm. 1
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Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL
Blood
2018
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Changes in DNA methylation related to male infertility
Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine (Elsevier), pp. 189-207
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Distinct chromatin signatures of DNA hypomethylation in aging and cancer
Aging Cell, Vol. 17, Núm. 3
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Epigenetic dysregulation of TET2 in human glioblastoma
Oncotarget, Vol. 9, Núm. 40, pp. 25922-25934