MARIO
FERNANDEZ FRAGA
Profesor Asociado
Universitat de Barcelona
Barcelona, EspañaPublicaciones en colaboración con investigadores/as de Universitat de Barcelona (32)
2023
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
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Circulating miRNA expression in long-standing type 1 diabetes mellitus
Scientific Reports, Vol. 13, Núm. 1
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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
Cell Reports, Vol. 42, Núm. 8
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The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 878-895
2022
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Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies
Journal of the National Cancer Institute, Vol. 114, Núm. 3, pp. 436-445
2021
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Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome
Blood, Vol. 137, Núm. 7, pp. 994-999
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Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia
Journal of Clinical Investigation, Vol. 131, Núm. 13
2019
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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment
Nucleic Acids Research, Vol. 47, Núm. 10, pp. 5016-5037
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Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program
Acta Neuropathologica, Vol. 138, Núm. 6, pp. 1053-1074
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Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL
Blood
2018
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Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis
The Lancet Respiratory Medicine, Vol. 6, Núm. 10, pp. 771-781
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Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation
Epigenomics, Vol. 10, Núm. 7, pp. 903-924
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Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma
Human Molecular Genetics, Vol. 27, Núm. 17, pp. 3046-3059
2017
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DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes
Nanotoxicology, Vol. 11, Núm. 7, pp. 857-870
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Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus
Stem Cell Research, Vol. 21, pp. 137-140
2016
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Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
Stem Cell Reports, Vol. 7, Núm. 4, pp. 602-618
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Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
Nature Biotechnology, Vol. 34, Núm. 7, pp. 726-737
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα
Leukemia, Vol. 30, Núm. 3, pp. 674-682
2015
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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
Genome Research, Vol. 25, Núm. 1, pp. 27-40
2014
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Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a
Cell Reports, Vol. 8, Núm. 3, pp. 743-753