MARIO
FERNANDEZ FRAGA
Profesor Asociado
Jesús
Espada Regalado
Publicaciones en las que colabora con Jesús Espada Regalado (13)
2010
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Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
Aging Cell, Vol. 9, Núm. 6, pp. 947-957
2009
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The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer
Genome Research, Vol. 19, Núm. 3, pp. 438-451
2007
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Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
Nucleic Acids Research, Vol. 35, Núm. 7, pp. 2191-2198
2006
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Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
Oncogene, Vol. 25, Núm. 29, pp. 4116-4121
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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Núm. 23, pp. 8822-8827
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Release of hypoacetylated and trimethylated histone H4 is an epigenetic marker of early apoptosis
Journal of Biological Chemistry, Vol. 281, Núm. 19, pp. 13540-13547
2005
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Inactivation of the Lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma
Journal of Clinical Oncology, Vol. 23, Núm. 17, pp. 3940-3947
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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
Nature Genetics, Vol. 37, Núm. 4, pp. 391-400
2004
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A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors
Cancer Research, Vol. 64, Núm. 16, pp. 5527-5534
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Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells
Human Molecular Genetics, Vol. 13, Núm. 22, pp. 2753-2765
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Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern
Journal of Biological Chemistry, Vol. 279, Núm. 35, pp. 37175-37184
2003
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Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
EMBO Journal, Vol. 22, Núm. 23, pp. 6335-6345
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Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
Cancer Research, Vol. 63, Núm. 16, pp. 4984-4989