ISAAC
ANTOLIN GONZALEZ
Catedrático de Universidad
Publicaciones (64) Publicaciones de ISAAC ANTOLIN GONZALEZ
2024
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Endoplasmic reticulum regulation of glucose metabolism in glioma stem cells
International journal of oncology, Vol. 64, Núm. 1
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FLT3-ITD regulation of the endoplasmic reticulum functions in acute myeloid leukemia
Hematological Oncology, Vol. 42, Núm. 3
2021
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Regulation of cancer cell glucose metabolism is determinant for cancer cell fate after melatonin administration
Journal of Cellular Physiology, Vol. 236, Núm. 1, pp. 27-40
2020
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Role of glucose metabolism in the differential antileukemic effect of melatonin on wild-type and FLT3-ITD mutant cells
Oncology Reports, Vol. 44, Núm. 1, pp. 293-302
2018
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Inhibition of flt3 and pim kinases by ec-70124 exerts potent activity in preclinical models of acute myeloid leukemia
Molecular Cancer Therapeutics, Vol. 17, Núm. 3, pp. 614-624
2016
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Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin
Molecular and Cellular Endocrinology, Vol. 434, pp. 238-249
2015
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Melatonin cytotoxicity is associated to Warburg effect inhibition in Ewing sarcoma cells
PLoS ONE, Vol. 10, Núm. 8
2014
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Involvement of autophagy in melatonin-induced cytotoxicity in glioma-initiating cells
Journal of Pineal Research, Vol. 57, Núm. 3, pp. 308-316
2013
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Mechanisms involved in the pro-apoptotic effect of melatonin in cancer cells
International Journal of Molecular Sciences, Vol. 14, Núm. 4, pp. 6597-6613
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Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells
British Journal of Cancer, Vol. 108, Núm. 10, pp. 2005-2012
2012
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Cooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells
Journal of Neuroscience Research, Vol. 90, Núm. 9, pp. 1850-1860
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Fas/Fas ligand regulation mediates cell death in human Ewing's sarcoma cells treated with melatonin
British Journal of Cancer, Vol. 106, Núm. 7, pp. 1288-1296
2011
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Intracellular redox state as determinant for melatonin antiproliferative vs cytotoxic effects in cancer cells
Free Radical Research, Vol. 45, Núm. 11-12, pp. 1333-1341
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Regulation of the expression of death receptors and their ligands by melatonin in haematological cancer cell lines and in leukaemia cells from patients
Journal of Pineal Research, Vol. 50, Núm. 3, pp. 345-355
2010
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Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death
Cancer Letters, Vol. 287, Núm. 2, pp. 216-223
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Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: Potentiation of the extrinsic apoptotic pathway
Journal of Pineal Research, Vol. 48, Núm. 1, pp. 72-80
2008
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Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine
Journal of Neurochemistry, Vol. 107, Núm. 1, pp. 127-140
2007
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Antioxidants do not prevent acrylonitrile-induced toxicity
Toxicology Letters, Vol. 169, Núm. 3, pp. 236-244
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Involvement of protein kinase C in melatonin's oncostatic effect in C6 glioma cells
Journal of Pineal Research, Vol. 43, Núm. 3, pp. 239-244
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Melatonin prevents glutamate-induced oxytosis in the HT22 mouse hippocampal cell line through an antioxidant effect specifically targeting mitochondria
Journal of Neurochemistry, Vol. 100, Núm. 3, pp. 736-746