BIOSÍNTESIS DE COMPUESTOS BIOACTIVOS POR MICROORGANISMOS
BIOMIC
University of Cambridge
Cambridge, Reino UnidoPublicaciones en colaboración con investigadores/as de University of Cambridge (9)
2016
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A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors
Journal of the American Chemical Society, Vol. 138, Núm. 13, pp. 4342-4345
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Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics
Angewandte Chemie - International Edition, Vol. 55, Núm. 33, pp. 9639-9643
2006
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Biosynthesis of the angiogenesis inhibitor borrelidin: Directed biosynthesis of novel analogues
Chemical Communications, pp. 2341-2343
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Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 22, pp. 5814-5817
2004
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Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055: Cluster Analysis and Assignment of Functions
Chemistry and Biology, Vol. 11, Núm. 1, pp. 87-97
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Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tü4055: Insights into nitrile formation
Molecular Microbiology, Vol. 52, Núm. 6, pp. 1745-1756
2003
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Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase
Chemical Communications, Vol. 3, Núm. 22, pp. 2780-2782
2002
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Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase
Molecular Microbiology, Vol. 43, Núm. 5, pp. 1215-1225
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Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea
Molecular Microbiology, Vol. 44, Núm. 3, pp. 771-781