GRUPO DE QUÍMICA BIOORGÁNICA
BIOORGANICA
University of York
York, Reino UnidoPublicaciones en colaboración con investigadores/as de University of York (13)
2021
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The Reactivity of α-Fluoroketones with PLP Dependent Enzymes: Transaminases as Hydrodefluorinases
ChemCatChem, Vol. 13, Núm. 18, pp. 3967-3972
2020
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Asymmetric Synthesis of Primary and Secondary β-Fluoro-arylamines using Reductive Aminases from Fungi
ChemCatChem, Vol. 12, Núm. 9, pp. 2421-2425
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Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases
Chemical Science, Vol. 11, Núm. 19, pp. 5052-5057
2018
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A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
ACS Catalysis, Vol. 8, Núm. 12, pp. 11534-11541
2017
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A reductive aminase from Aspergillus oryzae
Nature Chemistry, Vol. 9, Núm. 10, pp. 961-969
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Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
Angewandte Chemie - International Edition, Vol. 56, Núm. 49, pp. 15589-15593
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Imine reductases (IREDs)
Current Opinion in Chemical Biology, Vol. 37, pp. 19-25
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NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application
Advanced Synthesis and Catalysis, Vol. 359, Núm. 12, pp. 2011-2025
2016
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Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination
Angewandte Chemie - International Edition, Vol. 55, Núm. 9, pp. 3144-3147
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Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue
ChemBioChem, Vol. 17, Núm. 24, pp. 2308-2311
2014
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Structures of alcohol dehydrogenases from Ralstonia and Sphingobium spp. Reveal the molecular basis for their recognition of 'bulky-bulky' ketones
Topics in Catalysis, Vol. 57, Núm. 5, pp. 356-365
2013
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Structure and activity of NADPH-dependent reductase Q1EQE0 from streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate
ChemBioChem, Vol. 14, Núm. 11, pp. 1372-1379
2012
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Structures of a γ-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 68, Núm. 10, pp. 1175-1180