Identification of neuropsychiatric symptoms in preclinical and prodromal stages in dementiasDevelopment of a screening test for mild behavioral impairment

  1. Cristóbal Pereira-Abello
  2. Marcelino Cuesta-Izquierdo
  3. Laudino López-Álvarez
  4. Alfonso García-Viejo
Revista:
Psicothema

ISSN: 0214-9915,  1886-144X

Año de publicación: 2024

Volumen: 36

Número: 1

Páginas: 91-99

Tipo: Artículo

DOI: 10.7334/PSICOTHEMA2023.40 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Psicothema

Resumen

Los síntomas neuropsiquiátricos (SNP) constituyen una dimensión psicopatológica de las enfermedades neurodegenerativas conformada por cambios en la personalidad, trastornos conductuales o alteraciones en funciones básicas como, entre otras, el apetito o el sueño. El objetivo de este estudio es la construcción y validación de un test de cribado para la identificación de estos SNP asociados a patologías neurodegenerativas en etapas preclínicas y prodrómicas y basado en los criterios ISTAART para el Deterioro Conductual Leve (DCoL). Método: Se empleó una muestra de 206 sujetos mayores de 55 años (117 cognitivamente sanos y 89 con Deterioro Cognitivo Leve) siendo el 69% mujeres, con una media de edad de 77 años (DT = 10,58). Resultados: La nueva escala desarrollada consta de 19 items y muestra una estructura unidimensional. La fiabilidad fue excelente (α = .94 y Ω = .97) y se observaron evidencias de validez convergente con el test MBI-C con una correlación de .88 y la NPI-Q con .82. Además, muestra una buena sensibilidad de .88 y especificidad de .80. Conclusiones: La escala desarrollada permite evaluar los SNP en el DCoL mostrando buenas propiedades psicométricas y constituyendo una herramienta muy útil en el diagnóstico precoz de las patologías neurodegenerativas

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