Access to new (Cat)[Cu(CF3)2] complexes as efficient trifuoromethylating agents in the activation of aryl halides

  1. Carlota Odena 1
  2. Sara Martínez de Salinas 1
  3. Mónica H. Pérez-Temprano 1
  1. 1 Institut Català d’Investigació Química (ICIQ)
Revista:
Revista de la Societat Catalana de Química

ISSN: 2013-9853,  1576-8961

Año de publicación: 2020

Número: 19

Páginas: 21-31

Tipo: Artículo

DOI: 10.2436/20.2003.01.113 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Revista de la Societat Catalana de Química

Resumen

In this paper, the formation of bis(trifluoromethyl)cuprate complexes through a transmetalation reaction using analogous silver complexes and different copper(I) sources is discussed. The rapid, selective and in situ synthesis of these complexes has been developed from the reaction of (Cat)[Ag(CF3)2] and CuI under mild reaction conditions. Subsequently, their potential as trifluoromethylating agents in the formation of C-CF3 bonds using different model substrates such as aryl halides that contain Csp2-I, Csp2-Br and Csp3-Br bonds has been evaluated. It is worth mentioning that this is the first time that the capability of these species has been demonstrated, since their reactivity had been neglected to date.

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