Neurocognitive Functioning in Adolescents at Risk for Mental Health Problems
- Rebeca Aritio-Solana 1
- Eduardo Fonseca-Pedrero 1
- Alicia Pérez-Albéniz 2
- Oliver Mason 1
- Javier Ortuño-Sierra 1
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1
Universidad de La Rioja
info
- 2 Surrey University
ISSN: 0214-9915, 1886-144X
Año de publicación: 2022
Volumen: 34
Número: 2
Páginas: 259-265
Tipo: Artículo
Otras publicaciones en: Psicothema
Resumen
Antecedentes: el objetivo principal del estudio fue evaluar el funcionamiento neurocognitivo en adolescentes con alto riesgo psicométrico de presentar problemas de salud mental. Método: se seleccionó una muestra de 48 participantes con alto riesgo de trastornos mentales y un grupo de comparación de 48 adolescentes emparejados por edad y género a partir de la muestra total de 1.509 adolescentes. Se administró el Cuestionario de Capacidades y Dificultades y la Batería Neurocognitiva Computerizada de la Universidad de Pensilvania para población infantil y adolescente (incluidas 14 tareas que evalúan cinco dominios neurocognitivos: funciones ejecutivas, memoria episódica, cognición compleja, cognición social y velocidad sensoriomotora). Resultados: en relación con el grupo de comparación, los participantes de alto riesgo mostraron diferencias significativas en casi todos los dominios neurocognitivos. Conclusiones: estos hallazgos demuestran que diferentes alteraciones neurocognitivas pueden manifestarse en adolescentes con alto riesgo psicométrico de presentar problemas de salud mental antes de la aparición de dificultades psicológicas más graves.
Referencias bibliográficas
- Agerup, T., Lydersen, S., Wallander, J., & Sund, A. M. (2015). Associations Between Parental Attachment and Course of Depression Between Adolescence and Young Adulthood. Child Psychiatry and Human Development, 46(4), 632-642. https://doi.org/10.1007/s10578-014- 0506-y
- Basten, M. M. G. J., Althoff, R. R., Tiemeier, H., Jaddoe, V. W. V., Hofman, A., Hudziak, J. J., Verhulst, F. C., & van der Ende, J. (2013). The Dysregulation Profile in Young Children: Empirically Defined Classes in the Generation R Study. Journal of the American Academy of Child & Adolescent Psychiatry, 52(8), 841-850.e2. https://doi.org/10.1016/j. jaac.2013.05.007
- Blakemore, S.-J., & Robbins, T. W. (2012). Decision-making in the adolescent brain. Nature Neuroscience, 15(9), 1184-1191. https://doi.org/10.1038/nn.3177
- Blanken, L. M. E., White, T., Mous, S. E., Basten, M., Muetzel, R. L., Jaddoe, V. W. V., Wals, M., van der Ende, J., Verhulst, F. C., & Tiemeier, H. (2017). Cognitive functioning in children with internalising, externalising and dysregulation problems: A population-based study. European Child & Adolescent Psychiatry, 26(4), 445-456. https://doi.org/10.1007/s00787-016-0903-9
- Calkins, M. E., Merikangas, K. R., Moore, T. M., Burstein, M., Behr, M. A., Satterthwaite, T. D., Ruparel, K., Wolf, D. H., Roalf, D. R., Mentch, F. D., Qiu, H., Chiavacci, R., Connolly, J. J., Sleiman, P. M. A., Gur, R. C., Hakonarson, H., & Gur, R. E. (2015). The Philadelphia Neurodevelopmental Cohort: Constructing a deep phenotyping collaborative. Journal of Child Psychology and Psychiatry and Allied Disciplines, 56(12), 1356-1369. https://doi.org/10.1111/jcpp.12416
- Caspi, A., Houts, R. M., Ambler, A., Danese, A., Elliott, M. L., Hariri, A., Harrington, H. L., Hogan, S., Poulton, R., Ramrakha, S., Rasmussen, L. J. H., Reuben, A., Richmond-Rakerd, L., Sugden, K., Wertz, J., Williams, B. S., & Moffitt, T. E. (2020). Longitudinal Assessment of Mental Health Disorders and Comorbidities Across 4 Decades Among Participants in the Dunedin Birth Cohort Study. JAMA Network Open, 3(4), e203221. https://doi.org/10.1001/JAMANETWORKOPEN.2020.3221
- Cotter, J. (2018). Social cognitive dysfunction as a clinical marker: A systematic review of meta-analyses across 30 clinical conditions. Neuroscience Biobehavioral Review, 84, 92-99.
- Drabick, D. A. G., & Kendall, P. C. (2010). Developmental Psychopathology and the Diagnosis of Mental Health Problems among Youth. Clinical Psychology: A Publication of the Division of Clinical Psychology of the American Psychological Association, 17(4), 272-280. https://doi.org/10.1111/j.1468-2850.2010.01219.x
- Dray, J., Bowman, J., Campbell, E., Freund, M., Wolfenden, L., Hodder, R. K., McElwaine, K., Tremain, D., Bartlem, K., Bailey, J., Small, T., Palazzi, K., Oldmeadow, C., & Wiggers, J. (2017). Systematic Review of Universal Resilience-Focused Interventions Targeting Child and Adolescent Mental Health in the School Setting. Journal of the American Academy of Child & Adolescent Psychiatry, 56(10), 813-824. https://doi.org/10.1016/j.jaac.2017.07.780
- Fonseca-Pedrero, E. (2021). Manual de tratamientos psicológicos Infancia y adolescencia [Manual of psychological treatments Childhood and adolescence]. Pirámide.
- Fonseca-Pedrero, E., Debbané, M., Rodríguez-Testal, J. F., Cohen, A. S., Docherty, A. R., & Ortuño-Sierra, J. (2021). Schizotypy: The way ahead. Psicothema, 33(1), 16-27 https://doi.org/10.7334/psicothema2019.285
- Fonseca-Pedrero, E., Inchausti, F., Pérez-Gutiérrez, L., Aritio Solana, R., Ortuño-Sierra, J., Sánchez-García, M. Á., Lucas-Molina, B., Domínguez, C., Foncea, D., Espinosa, V., Gorría, A., Urbiola-Merina, E., Fernández, M., Merina Díaz, C., Gutiérrez, C., Aures, M., Campos, M. S., Domínguez-Garrido, E., & Pérez de Albéniz Iturriaga, A. (2017). Suicidal ideation in a community-derived sample of Spanish adolescents. Revista de Psiquiatria y Salud Mental, 11(2), 76-85. https://doi.org/10.1016/j.rpsm.2017.07.004
- Fonseca-Pedrero, E., Paino-Piñeiro, M., Lemos-Giráldez, S., Villazón-García, U., & Muñiz, J. (2009). Validation of the Schizotypal Personality Questionnaire-Brief Form in adolescents. Schizophrenia Research, 111(1-3), 53-60. https://doi.org/10.1016/j.schres.2009.03.006
- Fonseca-Pedrero, E., Pérez-Álvarez, M., Al-Halabí, S., Inchausti, F., López-Navarro, E. R., Muñiz, J., Lucas-Molina, B., Pérez-Albéniz, A., Baños Rivera, R., Cano-Vindel, A., Gimeno-Peón, A., Prado-Abril, J., González-Menéndez, A., Valero, A. V, Priede, A., González-Blanch, C., Ruiz-Rodríguez, P., Moriana, J. A., Gómez, L. E., … Montoya-Castilla, I. (2021). Empirically supported psychological treatments for children and adolescents: State of the art. Psicothema, 33(3), 386-398. https://doi.org/10.7334/PSICOTHEMA2021.56
- Fusar-Poli, P., Deste, G., Smieskova, R., Barlati, S., Yung, A. R., Howes, O., Stieglitz, R.-D., Vita, A., McGuire, P., & Borgwardt, S. (2012). Cognitive Functioning in Prodromal Psychosis. Archives of General Psychiatry, 69(6), 562-571. https://doi.org/10.1001/archgenpsychiatry.2011.1592
- Gottesman, I. I., & Gould, T. D. (2003). The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions. American Journal of Psychiatry, 160(4), 636-645. https://doi.org/10.1176/appi. ajp.160.4.636
- Gur, R. C., Calkins, M. E., Satterthwaite, T. D., Ruparel, K., Bilker, W. B., Moore, T. M., Savitt, A. P., Hakonarson, H., & Gur, R. E. (2014). Neurocognitive Growth Charting in Psychosis Spectrum Youths. JAMA Psychiatry, 71(4), 366. https://doi.org/10.1001/ jamapsychiatry.2013.4190
- Gur, R. C., Richard, J., Calkins, M. E., Chiavacci, R., Hansen, J. A., Bilker, W. B., Loughead, J., Connolly, J. J., Qiu, H., Mentch, F. D., Abou-Sleiman, P. M., Hakonarson, H., & Gur, R. E. (2012). Age group and sex differences in performance on a computerized neurocognitive battery in children age 8-21. Neuropsychology, 26(2), 251-265. https://doi.org/10.1037/A0026712
- Gur, R. C., Richard, J., Hughett, P., Calkins, M. E., Macy, L., Bilker, W. B., Brensinger, C., & Gur, R. E. (2010). A cognitive neurosciencebased computerized battery for efficient measurement of individual differences: Standardization and initial construct validation. Journal of Neuroscience Methods, 187(2), 254-262. https://doi.org/10.1016/j. jneumeth.2009.11.017
- Hobson, C. W., Scott, S., & Rubia, K. (2011). Investigation of cool and hot executive function in ODD/CD independently of ADHD. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 52(10), 1035- 1043. https://doi.org/10.1111/j.1469-7610.2011.02454.x
- IBM Corp Released (2013). IBM SPSS Statistics for Windows, Version 22.0. IBM Corp.
- Loge, D. V., Staton, R. D., & Beatty, W. W. (1990). Performance of Children with ADHD on Tests Sensitive to Frontal Lobe Dysfunction. Journal of the American Academy of Child & Adolescent Psychiatry, 29(4), 540- 545. https://doi.org/10.1097/00004583-199007000-00006
- McGrath, J. J., Saha, S., Al-Hamzawi, A. O., Alonso, J., Andrade, L., Borges, G., Bromet, E. J., Browne, M. O., Bruffaerts, R., Caldas De Almeida, J. M., Fayyad, J., Florescu, S., De Girolamo, G., Gureje, O., Hu, C., De Jonge, P., Kovess-Masfety, V., Lepine, J. P., Lim, C. C. W., … Kessler, R. C. (2016). Age of onset and lifetime projected risk of psychotic experiences: Cross-national data from the world mental health survey. Schizophrenia Bulletin, 42(4), 933-941. https://doi.org/10.1093/schbul/sbw011
- McQuade, J. D., Murray-Close, D., Shoulberg, E. K., & Hoza, B. (2013). Working memory and social functioning in children. Journal of Experimental Child Psychology, 115(3), 422-435. https://doi.org/10.1016/j.jecp.2013.03.002
- Merikangas, A. K., Cui, L., Calkins, M. E., Moore, T. M., Gur, R. C., Gur, R. E., & Merikangas, K. R. (2017). Neurocognitive performance as an endophenotype for mood disorder subgroups. Journal of Affective Disorders, 215, 163-171. https://doi.org/10.1016/j.jad.2017.03.021
- Mewton, L., Hodge, A., Gates, N., Visontay, R., & Teesson, M. (2017). The Brain Games study: protocol for a randomised controlled trial of computerised cognitive training for preventing mental illness in adolescents with high-risk personality styles. BMJ Open, 7(9), e017721. https://doi.org/10.1136/bmjopen-2017-017721
- Moore, T. M., Gur, R. C., Thomas, M. L., Brown, G. G., Nock, M. K., Savitt, A. P., Keilp, J. G., Heeringa, S., Ursano, R. J., & Stein, M. B. (2017). Development, Administration, and Structural Validity of a Brief, Computerized Neurocognitive Battery. Assessment, 107319111668982. https://doi.org/10.1177/1073191116689820
- Moore, T. M., Reise, S. P., Gur, R. E., Hakonarson, H., & Gur, R. C. (2015). Psychometric properties of the Penn Computerized Neurocognitive Battery. Neuropsychology, 29(2), 235-246. https://doi.org/10.1037/ neu0000093
- Muñiz, J., Elosua, P., & Hambleton, R. K. (2013). Directrices para la traducción y adaptación de los tests: segunda edición [International Test Commission Guidelines for test translation and adaptation: Second edition]. Psicothema, 25(2), 151-157. https://doi.org/10.7334/ psicothema2013.24
- Ortuño-Sierra, J., Fonseca-Pedrero, E., Paino, M., Sastre I Riba, S., & Muñiz, J. (2015). Screening mental health problems during adolescence: Psychometric properties of the Spanish version of the strengths and difficulties Questionnaire. Journal of Adolescence, 38(2), 49-56. https://doi.org/10.1016/j.adolescence.2014.11.001
- Polanczyk, G. V., Fatori, D., & Matijasevich, A. (2018). Integrating child and adolescent psychiatry and the field of early childhood development. European Child & Adolescent Psychiatry, 27(2), 137-138. https://doi.org/10.1007/s00787-018-1131-2
- Polanczyk, G. V., Salum, G. A., Sugaya, L. S., Caye, A., & Rohde, L. A. (2015). Annual research review: A meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. Journal of Child Psychology and Psychiatry, 56, 345-365.
- Santamaría-García, H., Baez, S., Gómez, C., Rodríguez-Villagra, O., Huepe, D., Portela, M., Reyes, P., Klahr, J., Matallana, D., & Ibanez, A. (2020). The role of social cognition skills and social determinants of health in predicting symptoms of mental illness. Translational Psychiatry, 10(1), 1-13. https://doi.org/10.1038/s41398-020-0852-4
- Schoemaker, K., Bunte, T., Espy, K. A., Deković, M., & Matthys, W. (2014). Executive functions in preschool children with ADHD and DBD: An 18-month longitudinal study. Developmental Neuropsychology, 39(4), 302-315. https://doi.org/10.1080/87565641.2014.911875
- Schoemaker, M. M., Niemeijer, A. S., Flapper, B. C. T., & Smits-Engelsman, B. C. M. (2012). Validity and reliability of the Movement Assessment Battery for Children-2 Checklist for children with and without motor impairments. Developmental Medicine and Child Neurology, 54(4), 368-375. https://doi.org/10.1111/j.1469-8749.2012.04226.x
- Spear, L. P. (2013). Adolescent neurodevelopment. The Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine, 52(2 Suppl 2), S7-13. https://doi.org/10.1016/j.jadohealth.2012.05.006