Hacia una herramienta de cribado temprano del trastorno del espectro del autismo (TEA)

  1. Acevedo Díaz, Gloria 1
  2. Camero Fernández, Raquel 1
  3. Fernández Prada, Mónica 1
  4. Andrés Suárez, Javier de 2
  5. González-Rodríguez, Martín 2
  6. Fernández-Lanvin, Daniel 2
  1. 1 Equipo de investigación de ADANSI (Asociación de Familiares y Personas con Autismo de Asturias)
  2. 2 Equipo de investigación HCI del grupo Computational Reflection de la Universidad de Oviedo
Revista:
Siglo Cero: Revista Española sobre Discapacidad Intelectual

ISSN: 2530-0350

Ano de publicación: 2022

Volume: 53

Número: 1

Páxinas: 71-93

Tipo: Artigo

DOI: 10.14201/SCERO20225317193 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Siglo Cero: Revista Española sobre Discapacidad Intelectual

Resumo

In recent years, eye-tracking methodology technique has been the objectof study used in different investigations as a potential objective measure of the diagnosis ofASD. In the present study, a total of 15 stimulus videos have been prepared. These are divided into four blocks to design an objective test with simple and rapid application, by using an eye-tracker device, which allows an early diagnosis of ASD. To do so, we measured a sample made up of 148 subjects, 74 subjects with ASD and 74 with typical development. The results confirm that it is possible to configure a software that, after analysing the gaze records of a baby obtained with an eye-tracker device, automatically provides us with its probability of presenting an “ASD or no ASD Gaze Pattern”. With the tasks presented here, after analysing the sensitivity of each video and each variable, statistically significant results have been obtained in each of the stimulus videos. Based on that output, it can be concluded that the eye-tracking methodology with the use of the stimuli designed here can be used as an objective and effective diagnostic method for ASD.

Referencias bibliográficas

  • ACEVEDO, G. (2020). Sobre el cerebro autista. Procedimiento de actuación temprana para niños y niñas con patrón de mirada diferente. Nieva ediciones.
  • ADANSI. (2021). Proyecto “Cómo mira tu bebé”. Recuperado de https://adansi.es/
  • DALTON, K. M., NACEWICZ, B. M., JOHNSTONE, T., SCHAEFER, H. S., GERNSBACHER, M. A., GOLDSMITH, H. H., ALEXANDER, A. L. y DAVIDSON, R. J. (2005). Gaze fixation and the neural circuitry of face processing in autism. Nature Neurosci-ence, 8(4), 519-526. https://doi.org/10.1038/nn1421
  • DAWSON, G., MELTZOFF, A. N., OSTERLING, J. y RINALDI, J. (1998). Neuropsychological correlates of early symptoms of autism. Child Development, 69(5), 1276-1285. https://doi.org/10.2307/1132265
  • DAWSON, G., MELTZOFF, A. N., OSTERLING, J., RINALDI, J. y BROWN, E. (1998). Children with autism fail to orient to naturally occurring social stimuli. Journal of Autism and Developmental Disorders, 28(6), 479-485. https://doi.org/10.1023/a:1026043926488
  • ESCUDERO, A. J., CARRANZA, J. A. y HUESCAR, E. (2013). Aparición y desarrollo de la Atención Conjunta en la infancia. Anales de Psicología, 29(2), 404-412. https://doi.org/10.6018/analesps.29.2.136871
  • FRAZIER, T. W., KLINGEMIER, E. W., PARIKH, S., SPEER, L., STRAUSS, M. S., ENG, C., HARDAN, A. Y. y YOUNGSTROM, E. A. (2018). Development and validation of objective and quantitative Eye Tracking-based measures of autism risk and symptom levels. Journal of the American Academy of Child and Adolescent Psychiatry, 57(11), 858-866. https://doi.org/10.1016/j.jaac.2018.06.023
  • HICKOK, G. y POEPPEL, D. (2000). Towards a functional neuroanatomy of speech perception. Trends Cognitive Scien-ces, 4(4), 131-138. https://doi.org/10.1016/s1364-6613(00)01463-7
  • HICKOK, G. y POEPPEL, D. (2007). The cortical organization of speech processing. Nature Reviews Neuroscience, 8(5), 393-402. https://doi.org/10.1038/nrn2113
  • HOWARD, P. L., ZHANG, L. y BENSON, V. (2019). What can eye movements tell us about subtle cognitive processing differences in autism? Vision (Basel), 3(2), 22. https://doi.org/10.3390/vision3020022
  • JACOB, P. y JEANNEROD, M. (2003). Ways of seeing: the scope and limits of visual cognition. Oxford Cognitive Scien-ce Series.
  • JELLEMA, T., BAKER, C. I., WICKER, B. y PERRETT, D. I. (2000). Neural representation for the perception of the intentiona-lity of actions. Brain and Cognition, 44(2), 280-302. https://doi.org/10.1006/brcg.2000.1231
  • KLIN, A., JONES, W., SCHULTZ, R., VOLKMAR, F. y COHEN, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychia-try, 59(9), 809-816. https://doi.org/10.1001/archpsyc.59.9.809
  • KLIN, A., LIN, D. J., GORRINDO, P., RAMSAY, G. y JONES, W. (2009). Two-year-olds with autism orient to non-social con-tingencies rather than biological motion. Nature, 459(7244), 257-261. https://doi.org/10.1038/nature07868
  • LEWKOWICZ, D. J. y HANSEN-TIFT, A. M. (2012). Infants deploy selective attention to the mouth of a talking face when learning speech. Proceedings of the National Academy of Sciences, 109(5), 1431-1436. https://doi.org/10.1073/pnas.1114783109
  • LORD, C., RUTTER, M., DILAVORE, P. C., RISI, S., GOTHAM, K. y BISHOP, S. L. (2013). Autism Diagnostic Observation Schedu-le, Second Edition (ADOS-2) Manual (Part I): Modules 1-4. Western Psychological Services. [Spanish version: LORD, C., RUTTER, M., DILAVORE, P. C., RISI, S., GOTHAM, K., BISHOP, S. L., LUYSTER, R. J. y GUTHRIE, W. (2015). Escala de Observación para el Diagnóstico del Autismo. ADOS-2. TEA].
  • MARISCAL, S. y GALLEGO, C. (2013). La imitación como herramienta para investigar y evaluar el desarrollo lingüístico temprano: un estudio piloto de repetición de palabras y pseudopalabras. Revista de Investigación en Logo-pedia, 3(1), 53-75.
  • MATERNA, S., DICKE, P. W. y THIER, P. (2008). Dissociable roles of the superior temporal sulcus and the intraparietal sulcus in joint attention: a functional magnetic resonance imaging study. Journal of Cognitive Neuroscience, 20(1), 108-119. https://doi.org/10.1162/jocn.2008.20.1.108
  • MILNER, A. D. y GOODALE, M. A. (1995). The visual brain in action. Oxford Psychology Series.
  • MURIAS, M., MAJOR, S., DAVLANTIS, K., FRANZ, L., HARRIS, A., RARDIN, B., SABATOS-DEVITO, M. y DAWSON, G. (2018). Validation of eye-tracking measures of social attention as a potential biomarker for autism clinical trials. Autism Re-search, 11(1), 166-174. https://doi.org/10.1002/aur.1894
  • OSTERLING, J. y DAWSON, G. (1994). Early recognition of children with autism: a study of first birthday home videota-pes. Journal of Autism and Developmental Disorders, 24(3), 247-257. https://doi.org/10.1007/BF02172225
  • PELPHREY, K. A., SASSON, N. J., REZNICK, J. S., PAUL, G., GOLDMAN, B. D. y PIVEN, J. (2002). Visual scanning of faces in au-tism. Journal Autism and Developmental Disorders, 32, 249-261. https://doi.org/10.1023/A:1016374617369
  • PERRETT, D. I., SMITH, P. A. J., POTTER, D. D., MISTLIN, A. J., HEAD, A. S., MILNER, A. D. y JEEVES, M. A. (1985). Visual cells in the temporal cortex sensitive to face view and gaze direction. Biological Sciences, 223(1232), 293-317. https://doi.org/10.1098/rspb.1985.0003
  • RIVIÈRE, Á. (2001). Autismo, orientaciones para la intervención educativa. Trotta.
  • RIZZOLATTI, G. y FABBRI-DESTRO, M. (2010). Mirror neurons: from discovery to autism. Experimental Brain Research, 200(3-4), 223-237. https://doi.org/10.1007/s00221-009-2002-3
  • SHIC, F., MACARI, S. y CHAWARSK, K. (2014). Speech disturbs face scanning in 6-month olds who develop Autism Spectrum Disorder. Biological Psychiatry, 75(3), 231-237. https://doi.org/10.1016/j.biopsych.2013.07.009
  • TENENBAUM, E. J., SOBEL, D. M., SHEINKOPF, S. J., SHAH, R. J., MALLE, B. F. y MORGAN, J. L. (2015). Attention to the mouth and gaze following in infancy predict language development. Journal of Child Language, 42(6), 1173-1190. https://doi.org/10.1017/S0305000914000725
  • WASS, S. V., JONES, J. H., GLIGA, T., SMITH, T. J., CHARMAN, T. y JOHNSON, M. H. (2015). Shorter spontaneous fixation dura-tions in infants with later emerging autism. Scientific Reports, 5, 1-8. https://doi.org/10.1038/srep08284
  • ZILBOVICIUS, M., MERESSE, I., CHABANE, N., BRUNELLE, F., SAMSON, Y. y BODDAERT, N. (2006). Autism, the superior temporal sulcus and social perception. Trends in Neurosciences, 29(7), 359-366. https://doi.org/10.1016/j.tins.2006.06.004
Fonte de datos: Dialnet