Valor predictor del cociente saturación hemoglobina/FiO2 en pacientes pediátricos con insuficiencia respiratoria aguda debida a neumonía tratados con ventilación no invasiva

Abstract

The use of non-invasive ventilation (NIV) in patients with hypoxemic acute respiratory failure (ARF) due to pneumonia is discussed. The most frequent cause of ARF was pneumonia and acute respiratory distress syndrome (ARDS) was the main cause of treatment failure. A good correlation between SF ratio (SpO2/FiO2) and PF ratio (paO2/FiO2) was recently confirmed. We aimed to evaluate if the SF ratio is a reliable predictive factor for NIV failure in pediatric patients with moderate hypoxemic ARF due to pneumonia and could classify ARDS according to the recent Berlin definition (mild, moderate and severe) to identify high-risk children. Our NIV success rate was 77%. SF ratio and heart rate at two hours were found to be independent predictors of NIV failure. The diagnosis of ARDS based on the SF ratio was not identified as an independent NIV outcome predictor. However, it may be useful in classifying high-risk children.