Qué debe saber el médico de primaria sobre los nuevos marcadores en el cáncer de próstata
- A. Jalón Monzón 1
- M. Alvarez Múgica 2
- M. Jalón Monzón 3
- S. Escaf Barmadah 1
- 1 Hospital Universitario Central de Asturias (HUCA), Oviedo (Asturias), España
- 2 Hospital Valle del Nalón, Langreo (Asturias), España
- 3 Centro de Salud de Contrueces, Gijón (Asturias), España
ISSN: 1138-3593
Año de publicación: 2018
Número: 6
Páginas: 430-438
Tipo: Artículo
Otras publicaciones en: Semergen: revista española de medicina de familia
Resumen
La utilización del antígeno prostático específico como herramienta diagnóstica en el cribado del cáncer de próstata se ve reflejada en un incremento en la incidencia, un incremento en el diagnóstico de cánceres más precoces y un aumento en los tratamientos con intención curativa, aun a costa de un sobretratamiento. Sabemos, por datos recogidos en la literatura, que no todo paciente con antígeno prostático específico elevado necesita biopsia, y que no todo paciente con diagnóstico de cáncer de próstata necesita tratamiento. Con los nuevos marcadores prostáticos emergentes vamos a tratar de mejorar la especificidad del antígeno prostático específico en la zona gris (4-10 ng/ml) evitando biopsias innecesarias, de mejorar la sensibilidad en la detección de cáncer de próstata significante con antígeno prostático específico bajo y a intentar reducir el riesgo de sobretratamiento. Por otro lado, los biomarcadores pronósticos con test genómicos nos van a ayudar a elegir la mejor opción terapéutica para el paciente.
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