Use of cultured human epithelium for coveragea defect of radial forearm free flap donor site

  1. Lorena Gallego López 2
  2. Luis Manuel Junquera Gutiérrez 3
  3. P.M. Villareal Renedo 2
  4. Ignacio Peña-González 2
  5. Alvaro Meana 1
  1. 1 Centro Comunitario de Sangre y Tejidos de Asturias
  2. 2 Hospital central de Oviedo
  3. 3 Universidad de Oviedo
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    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

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Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2010

Volumen: 15

Número: 1

Páginas: 13

Tipo: Artículo

DOI: 10.4317/MEDORAL.15.E58 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumen

The radial forearm free flap has been popular in many areas of reconstructive surgery. Despite the many attributes of this flap in maxillofacial reconstruction, one of the disadvantages has been the morbidity of the donor site. Allogeneic cultured epidermis has been successfully applied on large second degree burns and on chronic leg ulcers. Autologous human keratinocytes and fibroblast equivalents can be cultured in-vitro from a small skin sample in order to produce a sufficient amount of epithelial autografts to cover the large defects of third-degree burn wounds. Interestingly, transplanted cultured epidermis retains characteristics of the original donor site. We report a case of a patient who underwent skin replacement by cultured epithelial autograft after wound breakdown occurred in the forearm donor site during the early postoperative period. This method could represent an auspicious alternative to conventional grafting methods for forearm free flap reconstruction. To the best of our knowledge, skin replacement by cultured epithelial autografts in this region has not been extensively described in the literature.

Fuente de los datos: Dialnet