Uso de la Gabapentina en odontología

Abstract

The following paper tries to update Gabapentin, concerning its mechanism of action, pharmakinetics, dosage, interactions, contraindications, and general indications and its use clinical dental practice. Material and Method. A bibliographical review was performed, examining scientific publications, books and texts published in the last ten years. Results. The gabapentin reduces the release to the synaptic space of certain excitatory neurotransmiters and is involved in the nocioceptive transmission. lts side effects and pharmacological interactions are significantly inferior compared to other CNS drugs. lt's used commonly as an anticonvulsive agent. The utility of gabapentin use is documented in the treatment of neuropathic pain and other algias associated with inflammatorv processes. Likewise, its efficiency has been proven in chronic pain of the masticatory musculature. In relation to the treatment of Burning Mouth Syndrome conflictive results have been reported. Conclusions. More research is needed in this field, especially experiments designed to address the efficiency of gabapentin in the treatment TMJ disfunction and the burning mouth syndrome.