A combined measure for detection of schizotaxia

  1. Besteiro González, José Luis 1
  2. Paino Piñeiro, María de las Mercedes 1
  3. Lemos Giráldez, Serafín 1
  4. Inda Caro, Mercedes 1
  1. 1 Universidad de Oviedo
    info

    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 2004

Volumen: 16

Número: 2

Páginas: 299-308

Tipo: Artículo

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Otras publicaciones en: Psicothema

Resumen

This study falls within research on schizotaxia, or neurocognitive risk markers of schizophrenia spectrum disorders, and its usefulness for early prevention strategies. Two samples of 60 adults and 65 children and adolescents, with some genetic or psychosocial high-risk individuals among them, were examined to compare the relationship between schizotypy dimensions and risk factors, and neurocognitive performance. One of the most practical aspects of this study was the proposal of a combined and straightforward measure of liability to schizophrenia spectrum disorders, in contrast to the current high availability of neurocognitive markers. For that purpose, several psychometric analyses were made exploring schizotypy dimensions, as well as 16 measures of cortical functions (executive, attentional, working memory and general cognitive functioning tasks) in adults and 20 measures in adolescents. In keeping with previous research, our results hypothetically indicate that the most accurate measure of schizotaxia combines negative traits of schizotypy, in the range of percentile 90 or higher in the Introvertive Anhedonia subscale of the O-LIFE or percentile 85 or higher in the Negative Schizotypy subscale of the MSTQ and, on the other hand, a score of 5 or higher in a combined neurocognitive deficit scale in adults and 6 or higher in adolescents (the number of measures exceeding the threshold of deficit of the distribution scores). Moreover, some other independent measures of clinical and social function, and follow-up studies, are necessary to confirm the predictive validity of this measure of schizotaxia.

Referencias bibliográficas

  • Andreasen, N.C. (1983). Scale for the assessment of negative symptoms (SANS). Iowa City, IA: University of Iowa.
  • Birchwood, M., McGorry, P. and Jackson, H. (1997). Early intervention in schizophrenia. British Journal of Psychiatry, 170, 2-5.
  • Cornblatt, B., Lencz, T. and Obuchowski, M. (2002). The schizophrenia prodrome: Treatment and high-risk perspectives. Schizophrenia Research, 54, 177-186.
  • Cuevas-Yust, C., Perona-Garcelán, S. F. and Martínez-López, M.J. (2003). Tratamiento cognitivo-conductual de un paciente con diagnóstico de trastorno delirante (Cognitive-behavioral treatment of a patient diagnosed of delusional disorder). Psicothema, 15, 120-126.
  • Dinn, W.M., Harris, C.L., Aycicegi, A., Greene, P. and Andover, M.S. (2002). Positive and negative schizotypy in a student sample: Neurocognitive and clinical correlates. Schizophrenia Research, 56, 171-185.
  • Faraone, S.V., Green, A.I., Seidman, L.J. and Tsuang, M.T. (2001). «Schizotaxia»: Clinical implications and new directions for research. Schizophrenia Bulletin, 27, 1-18.
  • Faraone, S.V., Kremen, W.S., Lyons, M.J., Pepple, J.R., Seidman, L.J. and Tsuang, M.T. (1995). Diagnostic accuracy and linkage analysis: How useful are schizophrenia spectrum phenotypes? American Journal of Psychiatry, 152, 1.286-1.290.
  • Faraone, S.V., Seidman, L.J., Kremen, W.S., Pepple, J.R., Lyons, M.J. and Tsuang, M.T. (1995). Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: A diagnostic efficiency analysis. Journal of Abnormal Psychology, 104, 286-304.
  • Faraone, S.V., Seidman, L.J., Kremen, W.S., Toomey, R., Pepple, J.R. and Tsuang, M.T. (1999). Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: A four-year follow-up study. Journal of Abnormal Psychology, 108, 176-181.
  • Frith, C.D. (1992). The cognitive neuropsychology of schizophrenia. Hove, UK: Erlbaum.
  • Heaton, R.K. (1981). Wisconsin Card Sorting Test manual. Odessa, FL: Psychological Assessment Resources, Inc.
  • Johannenssen, J., Larsen, T., McGlashan, T. and Vaglum, P. (2000). Early intervention in psychosis: The TIPS-project, a multi-centre study in Scandinavia. In B. Martindale, A. Bateman, M. Crowe and F. Margison (Eds.), Psychosis: Psychological approaches and their effectiveness (pp. 210-234). London: Gaskell.
  • Johnson, M.K. and Raye, C.L. (1981). Reality monitoring. Psychological Review, 88, 67-85.
  • Kendler, K.S. (1985). Diagnostic approaches to schizotypal personality disorder: A historical perspective. Schizophrenia Bulletin, 11, 538-553.
  • Kendler, K.S., Neale, M.C. and Walsh, D. (1995). Evaluating the spectrum concept of schizophrenia in the Roscommon Family Study. American Journal of Psychiatry, 152, 749-754.
  • Kendler, K.S., Ochs, A.L., Gorman, A.M., Hewitt, J.K., Ross, D.E. and Mirsky, A.F. (1991). The structure of schizoptypy: A pilot multitrait twin study. Psychiatry Research, 36, 19-36.
  • Kwapil, T.R. (1998). Social anhedonia as a predictor of the development of schizophrenia-spectrum disorders. Journal of Abnormal Psychology, 107, 558-565.
  • Lemos-Giráldez, S., Inda-Caro, M., López-Rodrigo, A.M., Paíno-Piñeiro, M. and Besteiro-González, J.L. (2000). Assessment of essential components of schizotypy using neurocognitive measures. Psychology in Spain, 4, 183-194.
  • Lencz, T., Raine, A., Benishay, D.S., Mills, S. and Bird, L. (1995). Neuropsychological abnormalities associated with schizotypal personality. In A. Raine, T. Lencz and S.A. Mednick (Eds.), Schizotypal Personality (pp. 289-328). New York: Cambridge University Press.
  • Lenzenweger, M.F. (1994). Psychometric high-risk paradigm, perceptual aberrations, and schizotypy: An update. Schizophrenia Bulletin, 20, 121-135.
  • Lenzenweger, M.F. and Korfine, L. (1995). Tracking the taxon: On the latent structure and base rate of schizotypy. In A. Raine, T. Lencz and S.A. Mednick (Eds.), Schizotypal Personality (pp. 135-167). New York: Cambridge University Press.
  • Lenzenweger, M.F., Loranger, A.W., Korfine, L. and Neff, C. (1997). Detecting personality disorders in a nonclinical population: Application of a 2-stage procedure for case identification. Archives of General Psychiatry, 54, 345-351.
  • Martínez Suárez, P.C., Ferrando Piera, P.J., Lemos Giráldez, S., Inda Caro, M., Paíno Piñeiro, M. and López Rodrigo, A.M. (1997). Naturaleza y estructura del constructro esquizotipia. Análisis y Modificación de Conducta, 25, 615-637.
  • Mason, O., Claridge, G. and Jackson, M. (1995). New scales for the assessment of schizotypy. Personality and Individual Differences, 18, 7-13.
  • McCreey, C. and Claridge, G. (2002). Healthy schizotypy: The case of outof-the-body experiences. Personality and Individual Differences, 32, 141-154.
  • McGlashan, T.H., Miller, T.J. and Woods, S.W. (2001). Pre-onset detection and intervention research in schizophrenia psychoses: Current estimates of benefit and risk. Schizophrenia Bulletin, 27, 563-570.
  • McGorry, P.D., Edwards, J., Mihalopoulos, C., Harrigan, S.M., Jackson, H.J. and Bowes, G. (1996). EPPIC: An evolving system of early detection and optimal management. Schizophrenia Bulletin, 22, 305-326.
  • Meehl, P. (1995). Bootstraps taxometrics: Solving the classification problem in psychopathology. American Psychologist, 50, 266-275.
  • Meehl, P.E. (1962). Schizotaxia, schizotypy, schizophrenia. American Psychologist, 17, 827-838.
  • Meehl, P.E. (1989). Schizotaxia revisited. Archives of General Psychiatry, 46, 935-944.
  • Meehl, P.E. (1990). Toward an integrated theory of schizotaxia, schizotypy, and schizophrenia. Journal of Personality Disorders, 4, 1- 99.
  • Meehl, P.E. (1992). Factors and taxa, traits and types, differences of degree and differences in kind. Journal of Personality, 60, 117-174.
  • Meehl, P.E. (1993). The origins of some of my conjectures concerning schizophrenia. In L.J. Chapman, J.P. Chapman and D.C. Fowles (Eds.), Progress in experimental personality and psychopathology research (Vol. 16) (pp. 1-10). New York: Springer.
  • Meehl, P.E. (2001). Primary and secondary hypoedonia. Journal of Abnormal Psychology, 110, 188-193.
  • Olin, S. and Mednick, S.A. (1996). Risk factors of psychosis: Identifying vulnerable populations premorbidly. Schizophrenia Bulletin, 22, 223- 240.
  • Perona Garcelán, S. and Cuevas Yust, C. (2002). Aplicación de la terapia cognitivo conductual sobre las ideas delirantes y las alucinaciones en un sujeto con el diagnóstico de esquizofrenia (Application of cognitivebehavioural therapy to delusions ideas and hallucinations in a patient with the diagnosis of schizophrenia). Psicothema, 14, 26-33.
  • Rawlings, D. and Goldberg, M. (2001). Correlating a measure of sustained attention with a multidimensional measure of schizotypal traits. Personality and Individual Differences, 31, 421-431.
  • Reitan, R.M. (1958). Validity of the Trail Making Test as an indicator of organic brain damage. Perceptual and Motor Skills, 8, 271-276.
  • Siever, L.J., Bergman, A.J. and Keefe, R.S. (1995). The schizophrenia spectrum personality disorders. In S.R. Hirsch and D.R. Weinberger (Eds.), Schizophrenia (pp. 87-105). Cambridge, UK: Blackwell Science, Inc.
  • Siever, L.J., Koenigsberg, H.W., Harvey, P., Mitropoulou, V., Laruelle, M., Abi-Dargham, A., Goodman, M. and Buchsbaum, M. (2002). Cognitive and brain function in schizotypal personality disorder. Schizophrenia Research, 54, 157-167.
  • Stroop, J.R. (1935). Studies of interference in serial verbal reaction. Journal of Experimental Psychology, 18, 643-662.
  • Torgensen, S. (1985). Relationship of schizotypal personality disorder to schizophrenia: Genetics. Schizophrenia Bulletin, 11, 554-563.
  • Tsuang, M.T., Stone, W.S. and Faraone, S.V. (2000). Toward reformulating the diagnosis of schizophrenia. American Journal of Psychiatry, 157, 1.041-1.050.
  • Tsuang, M.T., Stone, W.S., Tarbox, S.I. and Faraone, S.V. (2002). An integration of schizophrenia with schizotypy: Identification of schizotaxia and implications for research on treatment and prevention. Schizophrenia Research, 54, 169-175.
  • Turkington, D., Kingdon, D. and Chadwick, P. (2003). Cognitive-behavioural therapy for schizophrenia: Filling the therapeutic vacuum. British Journal of Psychiatry, 183, 98-99.
Fuente de los datos: Dialnet