Maduración de los astrocitos del hipocampo de la rataposibles implicaciones conductuales

  1. Arias Pérez, Jorge Luis 1
  2. Vallejo Seco, Guillermo 1
  3. Conejo Jiménez, Nélida María 1
  4. González Pardo, Héctor 1
  5. Cimadevilla Redondo, José Manuel
  1. 1 Universidad de Oviedo
    info

    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 2003

Volumen: 15

Número: 2

Páginas: 216-220

Tipo: Artículo

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Otras publicaciones en: Psicothema

Resumen

Maduración de los astrocitos del hipocampo de la rata: posibles implicaciones conductuales. Diversos trabajos han mostrado que la astroglía juega un papel relevante en la fisiología del sistema nervioso central. Sin embargo, aún existen pocos estudios que se hayan centrado en el análisis de la población astroglial durante el desarrollo postnatal y la posible influencia de factores biológicos como el sexo. Empleando métodos estereológicos, se estimó el número total de astrocitos inmunorreactivos a la proteína ácida de la glía fibrilar (GFAP-ir) y su morfología en las áreas CA1 y CA3 del hipocampo de ratas macho y hembra a los 21 y 90 días de edad. El número de astrocitos GFAP-ir se incrementa significativamente con la edad en ambas áreas hipocámpicas en las hembras, pero sólo en el área CA3 en los machos. Además, no se observaron diferencias de género en ambas áreas hipocámpicas a los 21 días de edad, pero sí a los 90 días. Los cambios numéricos y diferencias de género en la población astroglial hipocámpica durante el desarrollo, se discuten en relación con su posible significado funcional.

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Fuente de los datos: Dialnet