Biología de Organismos y Sistemas
Departamento


Instituto Universitario de Oncologia del Principado de Asturias
Oviedo, España
2025
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Advancing Personalized Medicine in Alzheimer’s Disease: Liquid Biopsy Epigenomics Unveil APOE ε4-Linked Methylation Signatures
International Journal of Molecular Sciences, Vol. 26, Núm. 7
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Chromatin Preparation from Frozen Tissues for Chromatin Immunoprecipitation (ChIP) Assays
Methods in Molecular Biology (Humana Press Inc.), pp. 203-217
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Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
Cancer discovery, Vol. 15, Núm. 5, pp. 1037-1062
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DNA Methylation Analysis by Bisulfite Pyrosequencing of Mouse Embryonic Fibroblasts with Reprogramming Enhanced by Thyroid Hormones
Methods in Molecular Biology (Humana Press Inc.), pp. 131-147
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Epigenomic Profiling of Histone Posttranslational Modifications in Frozen Cancer Tissue Using CUT&RUN
Methods in Molecular Biology (Humana Press Inc.), pp. 229-243
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Epitranscriptomics in the Glioma Context: A Brief Overview
Cancers, Vol. 17, Núm. 4
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The immune checkpoint LILRB4 promotes immune evasion and is correlated with disease progression and secondary malignancies in chronic lymphocytic leukemia
Biomedicine and Pharmacotherapy, Vol. 189
2024
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A FokI-driven signal amplification platform for the simultaneous detection of multiple viral RNA pathogens
Sensors and Diagnostics, Vol. 3, Núm. 3, pp. 468-478
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A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment
Nature Communications, Vol. 15, Núm. 1
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A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma
eBioMedicine, Vol. 102
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Epigenetic Study of Cohort of Monozygotic Twins With Hypertrophic Cardiomyopathy Due to MYBPC3 (Cardiac Myosin-Binding Protein C)
Journal of the American Heart Association, Vol. 13, Núm. 21, pp. e035777
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Metformin and Glucose Concentration as Limiting Factors in Retinal Pigment Epithelial Cell Viability and Proliferation
International Journal of Molecular Sciences, Vol. 25, Núm. 5
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Novel 14q32.2 paternal deletion encompassing the whole DLK1 gene associated with Temple syndrome
Clinical Epigenetics, Vol. 16, Núm. 1
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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis
Metabolism: Clinical and Experimental, Vol. 158
2023
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A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin
Frontiers in Cell and Developmental Biology, Vol. 11
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
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CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer
Clinical Epigenetics, Vol. 15, Núm. 1
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Circulating miRNA expression in long-standing type 1 diabetes mellitus
Scientific Reports, Vol. 13, Núm. 1
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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
Cell Reports, Vol. 42, Núm. 8
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Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways
Cardiovascular Diabetology, Vol. 22, Núm. 1